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Web Design: Farnoosh Seifoddini
Biochemistry, Structural Biology, and Biophysics of Protein Synthesis
Publications
(see PubMed)
Colon-Ramos DA, Shenvi CL, Weitzel DH, Gan EC, Matts R, Cate JH, Kornbluth S.
(2006) Direct ribosomal binding by a cellular inhibitor of translation. Nat Struct Mol Biol. 2,103-111.
Shenvi CL, Dong KC, Friedman EM, Hanson JA, Cate JH.
(2005) Accessibility of 18S rRNA in human 40S subunits and 80S ribosomes at physiological magnesium
ion concentrations--implications for the study of ribosome dynamics. RNA. 12,1898-908.
Liau A, Karnik R, Majumdar A, Cate JH. (2005)
Mixing crowded biological solutions in milliseconds. Anal Chem. 23,7618-25.
Schuwirth BS, Borovinskaya MA, Hau CW, Zhang W, Vila-Sanjurjo A, Holton JM, Cate JH.
(2005) Structures of the bacterial ribosome at 3.5 A resolution. Science. 310,827-34.
Vila-Sanjurjo, A., Schuwrith, B.S.,
Hau,C.W. and Cate, J.H.D. (2004) Structural basis for the control of
translation initiation during stress. Nat. Struct. Molec. Biol. 11,1054-1059.
Ke, A., Zhou, K., Ding, F., Cate,
J.H. and Doudna, J.A. (2004) A conformational switch controls hepatitis delta
virus ribozyme catalysis. Nature 429, 201-205.
Vila-Sanjurjo, A., Ridgeway, W.K.,
Seymaner, V., Zhang, W., Santoso, S., Yu, K., and Doudna Cate, J.H. (2003)
X-ray crystal structures of the WT and a hyper-accurate ribosome from Eschericia
coli. PNAS 100, 8682-8687.
Noller, H.F., Yusupov, M.M.,
Yusupova, G.Z., Baucom, A. and Cate J.H.D. (2002) Translocation of tRNA during
protein synthesis. FEBS Letters 514, 11-16.
Cate, J.H.D. (2001) Construction of
low-resolution x-ray crystallographic electron density maps of the ribosome. Methods 25, 303-8.
Yusupova, G.Z., Yusupov, M.M., Cate,
J.H.D. & Noller, H.F. (2001) The path of messenger RNA through the
ribosome. Cell 106, 233-41.
Gregory, S.T., Cate, J.H. &
Dahlberg, A.E. (2001) Spontaneous Erythromycin Resistance Mutation in a 23S
rRNA Gene, rrlA, of the Extreme Thermophile Thermus thermophilus IB-21. J.
Bacteriol. 183, 4382-5.
Gregory, S.T., Cate, J.H. &
Dahlberg, A.E. (2001) Streptomycin-resistant and streptomycin-dependent mutants
of the extreme thermophile Thermus thermophilus. J. Molec. Biol. 309, 333-8.
Yusupov, M.M., Yusupova, G.Zh.,
Baucom, A., Lieberman, K., Earnest, T.N., Cate, J.H.D. and Noller, H.F. (2001)
Crystal Structure of the Ribosome at 5.5 Å Resolution. Science 292, 883-896.
Cate, J.H. and Doudna, J.A. (2000)
Solving large RNA structures by X-ray crystallography. Methods Enzymol. 317, 169-180.
Lancaster L., Culver G.M., Yusupova
G.Z., Cate J.H., Yusupov M.M., Noller H.F. (2000) The location of protein S8
and surrounding elements of 16S rRNA in the 70S ribosome from combined use of
directed hydroxyl radical probing and X-ray crystallography. RNA 6, 717-729.
Cate, J.H., Yusupov, M.M., Yusupova,
G.Zh., Earnest, T.N. and Noller, H.F. (1999) X-ray crystal structures of 70S
ribosome functional complexes. Science 285, 2095-2104.
Culver, G.M., Cate, J.H., Yusupova,
G.Zh., Yusupov, M.M. and Noller, H.F. (1999) Identification of an RNA-protein
bridge spanning the ribosomal subunit interface. Science 285, 2133-2135.
Strobel, S.A., Ortoleva-Donnelly,
L., Ryder, S.P., Cate, J.H. and Moncoeur, E. (1998) Complementary sets of
noncanonical base pairs mediate RNA helix packing in the group I intron active
site. Nature Struct. Biol.. 5, 60-66.
Basu, S., Rambo, R.P.,
Strauss-Soukup, J., Cate, J.H., Ferr-D'Amar, A.R., Strobel, S.A. and Doudna,
J.A. (1998) A specific monovalent metal ion integral to the AA platform of the
RNA tetraloop receptor. Nature Struct. Biol.. 5, 986-992.
Cate, J.H. and Doudna, J.A. (1998)
RNA structures determined by X-ray crystallography. Comprehensive Natural
Products Chemistry (D. Sll and S. Nishimura, Eds.) 6, 49-61.
Cate, J.H., Hanna, R.L. and Doudna,
J.A. (1997) A magnesium ion core at the heart of a ribozyme domain. Nature
Struct. Biol. 4, 553-558.
Cate, J.H. and Doudna, J.A. (1997) A
sparse matrix approach to crystallizing ribozymes and RNA motifs. Methods
Mol. Biol. 74, 379-386.
Doudna, J.A. and Cate, J.H. (1997)
RNA structure: crystal clear? Curr. Opin. Struct. Biol. 7, 310-316.
Cate, J.H., Gooding, A.R., Podell,
E., Zhou, K., Golden, B.L., Kundrot, C.E., Cech, T.R. and Doudna, J.A. (1996)
Crystal structure of a group I ribozyme domain: principles of RNA packing. Science 273, 1678-1685.
Cate, J.H., Gooding, A.R., Podell,
E., Zhou, K., Golden, B.L., Szewczak A.A., Kundrot, C.E., Cech, T.R. and
Doudna, J.A. (1996) RNA tertiary structure mediation by adenosine platforms. Science 273, 1696-1699.
Cate, J.H. and Doudna, J.A. (1996)
Metal binding sites in the major groove of a large ribozyme domain. Structure 4, 1221-1229.